BDBM50344189 (S)-2-(1-((S)-1-carboxy-2-(4-isobutyloxazol-2-yl)ethylcarbamoyl)cyclopentylamino)pentanoic acid::CHEMBL1778528

SMILES: CCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nc(CC(C)C)co1)C(O)=O)C(O)=O

InChI Key: InChIKey=QQXJEPZLFZCIMX-HOTGVXAUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Natriuretic peptides A (Homo sapiens (Human))	BDBM50344189 ((S)-2-(1-((S)-1-carboxy-2-(4-isobutyloxazol-2-yl)e...) Show SMILES CCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nc(CC(C)C)co1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C21H33N3O6/c1-4-7-15(18(25)26)24-21(8-5-6-9-21)20(29)23-16(19(27)28)11-17-22-14(12-30-17)10-13(2)3/h12-13,15-16,24H,4-11H2,1-3H3,(H,23,29)(H,25,26)(H,27,28)/t15-,16-/m0/s1	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of atrial natriuretic peptide				Bioorg Med Chem Lett 21: 3404-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.109 BindingDB Entry DOI: 10.7270/Q2PG1S2F
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50344189 ((S)-2-(1-((S)-1-carboxy-2-(4-isobutyloxazol-2-yl)e...) Show SMILES CCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nc(CC(C)C)co1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C21H33N3O6/c1-4-7-15(18(25)26)24-21(8-5-6-9-21)20(29)23-16(19(27)28)11-17-22-14(12-30-17)10-13(2)3/h12-13,15-16,24H,4-11H2,1-3H3,(H,23,29)(H,25,26)(H,27,28)/t15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase				Bioorg Med Chem Lett 21: 3404-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.109 BindingDB Entry DOI: 10.7270/Q2PG1S2F
					More data for this Ligand-Target Pair