BDBM50344192 (S)-2-(1-((S)-1-carboxy-2-(4-phenyloxazol-2-yl)ethylcarbamoyl)cyclopentylamino)-4-methoxybutanoic acid::CHEMBL1778531
SMILES: COCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nc(co1)-c1ccccc1)C(O)=O)C(O)=O
InChI Key: InChIKey=TZHXDQZJGFXLTE-IRXDYDNUSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Atrial natriuretic factor (Homo sapiens (Human)) | BDBM50344192 ((S)-2-(1-((S)-1-carboxy-2-(4-phenyloxazol-2-yl)eth...) | Reactome pathway KEGG GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of atrial natriuretic peptide | Bioorg Med Chem Lett 21: 3404-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.109 BindingDB Entry DOI: 10.7270/Q2PG1S2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50344192 ((S)-2-(1-((S)-1-carboxy-2-(4-phenyloxazol-2-yl)eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of neutral endopeptidase | Bioorg Med Chem Lett 21: 3404-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.109 BindingDB Entry DOI: 10.7270/Q2PG1S2F | |||||||||||
More data for this Ligand-Target Pair |