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BDBM50344196 (S)-2-(1-((S)-1-carboxy-2-(5-phenyl-1,3,4-oxadiazol-2-yl)ethylcarbamoyl)cyclopentylamino)-4-methoxybutanoic acid::CHEMBL1778535

SMILES: COCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nnc(o1)-c1ccccc1)C(O)=O)C(O)=O

InChI Key: InChIKey=CPPOMHFNVGKBRD-HOTGVXAUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344196   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Atrial natriuretic factor


(Homo sapiens (Human))
BDBM50344196
PNG
((S)-2-(1-((S)-1-carboxy-2-(5-phenyl-1,3,4-oxadiazo...)
Show SMILES COCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nnc(o1)-c1ccccc1)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C22H28N4O7/c1-32-12-9-15(19(27)28)24-22(10-5-6-11-22)21(31)23-16(20(29)30)13-17-25-26-18(33-17)14-7-3-2-4-8-14/h2-4,7-8,15-16,24H,5-6,9-13H2,1H3,(H,23,31)(H,27,28)(H,29,30)/t15-,16-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of atrial natriuretic peptide


Bioorg Med Chem Lett 21: 3404-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.109
BindingDB Entry DOI: 10.7270/Q2PG1S2F
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50344196
PNG
((S)-2-(1-((S)-1-carboxy-2-(5-phenyl-1,3,4-oxadiazo...)
Show SMILES COCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nnc(o1)-c1ccccc1)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C22H28N4O7/c1-32-12-9-15(19(27)28)24-22(10-5-6-11-22)21(31)23-16(20(29)30)13-17-25-26-18(33-17)14-7-3-2-4-8-14/h2-4,7-8,15-16,24H,5-6,9-13H2,1H3,(H,23,31)(H,27,28)(H,29,30)/t15-,16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of neutral endopeptidase


Bioorg Med Chem Lett 21: 3404-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.109
BindingDB Entry DOI: 10.7270/Q2PG1S2F
More data for this
Ligand-Target Pair