null

SMILES: O=C1Nc2ccccc2C1=Cc1c[nH]nc1-c1ccccc1

InChI Key: InChIKey=RINGOEHWKXCHGN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50344214 (3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-o...) Show SMILES O=C1Nc2ccccc2C1=Cc1c[nH]nc1-c1ccccc1 |w:10.12| Show InChI InChI=1S/C18H13N3O/c22-18-15(14-8-4-5-9-16(14)20-18)10-13-11-19-21-17(13)12-6-2-1-3-7-12/h1-11H,(H,19,21)(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of RSK2 (unknown origin) using AKRRRLSSLRA as substrate after 60 mins by fluorescence assay				Bioorg Med Chem 21: 1724-34 (2013) Article DOI: 10.1016/j.bmc.2013.01.047 BindingDB Entry DOI: 10.7270/Q2GQ704N
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50344214 (3-((3-phenyl-1H-pyrazol-4-yl)methylene)indolin-2-o...) Show SMILES O=C1Nc2ccccc2C1=Cc1c[nH]nc1-c1ccccc1 |w:10.12| Show InChI InChI=1S/C18H13N3O/c22-18-15(14-8-4-5-9-16(14)20-18)10-13-11-19-21-17(13)12-6-2-1-3-7-12/h1-11H,(H,19,21)(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
PharmaDesign, Inc. Curated by ChEMBL					Assay Description Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assay				Bioorg Med Chem 19: 3086-95 (2011) Article DOI: 10.1016/j.bmc.2011.04.008 BindingDB Entry DOI: 10.7270/Q2JQ11B3
					More data for this Ligand-Target Pair