BDBM50344244 1-cyclopropyl-N-((6-(2-fluoro-3-methoxyphenyl)pyrazin-2-yl)methyl)methanamine::CHEMBL1778997
SMILES: COc1cccc(c1F)-c1cncc(CNCC2CC2)n1
InChI Key: InChIKey=SPFOJSBLGPNTCT-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat)) | BDBM50344244 (1-cyclopropyl-N-((6-(2-fluoro-3-methoxyphenyl)pyra...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 602 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membrane | Bioorg Med Chem Lett 21: 3399-403 (2011) Article DOI: 10.1016/j.bmcl.2011.03.117 BindingDB Entry DOI: 10.7270/Q29887BK | |||||||||||
More data for this Ligand-Target Pair |