BDBM50344325 4-(6-chloropyridazin-3-yl)-2-isopropyl-7-methoxypyrazolo[1,5-a]pyridine::CHEMBL1779443

SMILES: COc1ccc(-c2ccc(Cl)nn2)c2cc(nn12)C(C)C

InChI Key: InChIKey=AONRSMASUDPLCX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50344325 (4-(6-chloropyridazin-3-yl)-2-isopropyl-7-methoxypy...) Show SMILES COc1ccc(-c2ccc(Cl)nn2)c2cc(nn12)C(C)C Show InChI InChI=1S/C15H15ClN4O/c1-9(2)12-8-13-10(11-5-6-14(16)18-17-11)4-7-15(21-3)20(13)19-12/h4-9H,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heriot-Watt University Curated by ChEMBL					Assay Description Inhibition of human PDE4B catalytic domain using cAMP/cGMP substrate				Bioorg Med Chem Lett 21: 3307-12 (2011) Article DOI: 10.1016/j.bmcl.2011.04.021 BindingDB Entry DOI: 10.7270/Q2X067C3
					More data for this Ligand-Target Pair