Found 5 hits for monomerid = 50344551 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50344551
(4-(Nitrooxy)butyl-4-(aminosulfonyl)benzoate | CHEM...)Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OCCCCO[N+]([O-])=O Show InChI InChI=1S/C11H14N2O7S/c12-21(17,18)10-5-3-9(4-6-10)11(14)19-7-1-2-8-20-13(15)16/h3-6H,1-2,7-8H2,(H2,12,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
U.O. Oculistica Az. USL 3
Curated by ChEMBL
| Assay Description Inhibition of human CA2 by CO2 hydration assay |
Bioorg Med Chem Lett 21: 3216-21 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.046 BindingDB Entry DOI: 10.7270/Q2GT5NHQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50344551
(4-(Nitrooxy)butyl-4-(aminosulfonyl)benzoate | CHEM...)Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OCCCCO[N+]([O-])=O Show InChI InChI=1S/C11H14N2O7S/c12-21(17,18)10-5-3-9(4-6-10)11(14)19-7-1-2-8-20-13(15)16/h3-6H,1-2,7-8H2,(H2,12,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
U.O. Oculistica Az. USL 3
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA12 catalytic domain by CO2 hydration assay |
Bioorg Med Chem Lett 21: 3216-21 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.046 BindingDB Entry DOI: 10.7270/Q2GT5NHQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM50344551
(4-(Nitrooxy)butyl-4-(aminosulfonyl)benzoate | CHEM...)Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OCCCCO[N+]([O-])=O Show InChI InChI=1S/C11H14N2O7S/c12-21(17,18)10-5-3-9(4-6-10)11(14)19-7-1-2-8-20-13(15)16/h3-6H,1-2,7-8H2,(H2,12,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
U.O. Oculistica Az. USL 3
Curated by ChEMBL
| Assay Description Inhibition of human CA4 by CO2 hydration assay |
Bioorg Med Chem Lett 21: 3216-21 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.046 BindingDB Entry DOI: 10.7270/Q2GT5NHQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50344551
(4-(Nitrooxy)butyl-4-(aminosulfonyl)benzoate | CHEM...)Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OCCCCO[N+]([O-])=O Show InChI InChI=1S/C11H14N2O7S/c12-21(17,18)10-5-3-9(4-6-10)11(14)19-7-1-2-8-20-13(15)16/h3-6H,1-2,7-8H2,(H2,12,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 165 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
U.O. Oculistica Az. USL 3
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA9 catalytic domain by CO2 hydration assay |
Bioorg Med Chem Lett 21: 3216-21 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.046 BindingDB Entry DOI: 10.7270/Q2GT5NHQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50344551
(4-(Nitrooxy)butyl-4-(aminosulfonyl)benzoate | CHEM...)Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OCCCCO[N+]([O-])=O Show InChI InChI=1S/C11H14N2O7S/c12-21(17,18)10-5-3-9(4-6-10)11(14)19-7-1-2-8-20-13(15)16/h3-6H,1-2,7-8H2,(H2,12,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 189 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
U.O. Oculistica Az. USL 3
Curated by ChEMBL
| Assay Description Inhibition of human CA1 by CO2 hydration assay |
Bioorg Med Chem Lett 21: 3216-21 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.046 BindingDB Entry DOI: 10.7270/Q2GT5NHQ |
More data for this Ligand-Target Pair | |