BDBM50344789 5-(2,5-dichlorophenyl)-N-(2,6-difluorophenyl)furan-2-carboxamide::CHEMBL1779898

SMILES: Fc1cccc(F)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl

InChI Key: InChIKey=JFLDHLNYZITLLD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50344789 (5-(2,5-dichlorophenyl)-N-(2,6-difluorophenyl)furan...) Show SMILES Fc1cccc(F)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C17H9Cl2F2NO2/c18-9-4-5-11(19)10(8-9)14-6-7-15(24-14)17(23)22-16-12(20)2-1-3-13(16)21/h1-8H,(H,22,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TE...				Bioorg Med Chem Lett 21: 3632-6 (2011) Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z
					More data for this Ligand-Target Pair