Found 5 hits for monomerid = 50344792 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sphingosine 1-phosphate receptor 4
(Homo sapiens (Human)) | BDBM50344792
(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)Show SMILES Cc1cc(O)cc(C)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C19H15Cl2NO3/c1-10-7-13(23)8-11(2)18(10)22-19(24)17-6-5-16(25-17)14-9-12(20)3-4-15(14)21/h3-9,23H,1-2H3,(H,22,24) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TE... |
Bioorg Med Chem Lett 21: 3632-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z |
More data for this Ligand-Target Pair | |
Sphingosine 1-phosphate receptor 1
(Homo sapiens (Human)) | BDBM50344792
(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)Show SMILES Cc1cc(O)cc(C)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C19H15Cl2NO3/c1-10-7-13(23)8-11(2)18(10)22-19(24)17-6-5-16(25-17)14-9-12(20)3-4-15(14)21/h3-9,23H,1-2H3,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of S1P1 receptor |
Bioorg Med Chem Lett 21: 3632-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z |
More data for this Ligand-Target Pair | |
Sphingosine 1-phosphate receptor 5
(Homo sapiens (Human)) | BDBM50344792
(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)Show SMILES Cc1cc(O)cc(C)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C19H15Cl2NO3/c1-10-7-13(23)8-11(2)18(10)22-19(24)17-6-5-16(25-17)14-9-12(20)3-4-15(14)21/h3-9,23H,1-2H3,(H,22,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of S1P5 receptor |
Bioorg Med Chem Lett 21: 3632-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z |
More data for this Ligand-Target Pair | |
Sphingosine 1-phosphate receptor 3
(Homo sapiens (Human)) | BDBM50344792
(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)Show SMILES Cc1cc(O)cc(C)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C19H15Cl2NO3/c1-10-7-13(23)8-11(2)18(10)22-19(24)17-6-5-16(25-17)14-9-12(20)3-4-15(14)21/h3-9,23H,1-2H3,(H,22,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of S1P3 receptor |
Bioorg Med Chem Lett 21: 3632-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z |
More data for this Ligand-Target Pair | |
Sphingosine 1-phosphate receptor 2
(Homo sapiens (Human)) | BDBM50344792
(5-(2,5-dichlorophenyl)-N-(4-hydroxy-2,6-dimethylph...)Show SMILES Cc1cc(O)cc(C)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C19H15Cl2NO3/c1-10-7-13(23)8-11(2)18(10)22-19(24)17-6-5-16(25-17)14-9-12(20)3-4-15(14)21/h3-9,23H,1-2H3,(H,22,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of S1P2 receptor |
Bioorg Med Chem Lett 21: 3632-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z |
More data for this Ligand-Target Pair | |