BDBM50344807 5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan-2-carboxamide::CHEMBL1779911

SMILES: Cc1ccc(C)c(c1)-c1ccc(o1)C(=O)Nc1c(C)cccc1C

InChI Key: InChIKey=FDAYNZPRBYZBIV-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50344807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50344807 (5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...) Show SMILES Cc1ccc(C)c(c1)-c1ccc(o1)C(=O)Nc1c(C)cccc1C Show InChI InChI=1S/C21H21NO2/c1-13-8-9-14(2)17(12-13)18-10-11-19(24-18)21(23)22-20-15(3)6-5-7-16(20)4/h5-12H,1-4H3,(H,22,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TE...				Bioorg Med Chem Lett 21: 3632-6 (2011) Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50344807 (5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...) Show SMILES Cc1ccc(C)c(c1)-c1ccc(o1)C(=O)Nc1c(C)cccc1C Show InChI InChI=1S/C21H21NO2/c1-13-8-9-14(2)17(12-13)18-10-11-19(24-18)21(23)22-20-15(3)6-5-7-16(20)4/h5-12H,1-4H3,(H,22,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human S1P4 receptor expressed in EDG6-bla U2OS cells coexpressing human endothelial differentiation gene 6 linked to GAL4-VP16...				Bioorg Med Chem Lett 21: 5470-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.132 BindingDB Entry DOI: 10.7270/Q2930TH3
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50344807 (5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...) Show SMILES Cc1ccc(C)c(c1)-c1ccc(o1)C(=O)Nc1c(C)cccc1C Show InChI InChI=1S/C21H21NO2/c1-13-8-9-14(2)17(12-13)18-10-11-19(24-18)21(23)22-20-15(3)6-5-7-16(20)4/h5-12H,1-4H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at S1P1 receptor				Bioorg Med Chem Lett 21: 5470-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.132 BindingDB Entry DOI: 10.7270/Q2930TH3
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM50344807 (5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...) Show SMILES Cc1ccc(C)c(c1)-c1ccc(o1)C(=O)Nc1c(C)cccc1C Show InChI InChI=1S/C21H21NO2/c1-13-8-9-14(2)17(12-13)18-10-11-19(24-18)21(23)22-20-15(3)6-5-7-16(20)4/h5-12H,1-4H3,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at S1P5 receptor				Bioorg Med Chem Lett 21: 5470-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.132 BindingDB Entry DOI: 10.7270/Q2930TH3
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50344807 (5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...) Show SMILES Cc1ccc(C)c(c1)-c1ccc(o1)C(=O)Nc1c(C)cccc1C Show InChI InChI=1S/C21H21NO2/c1-13-8-9-14(2)17(12-13)18-10-11-19(24-18)21(23)22-20-15(3)6-5-7-16(20)4/h5-12H,1-4H3,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at S1P3 receptor				Bioorg Med Chem Lett 21: 5470-4 (2011) Article DOI: 10.1016/j.bmcl.2011.06.132 BindingDB Entry DOI: 10.7270/Q2930TH3
					More data for this Ligand-Target Pair