BDBM50344994 2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid::CHEMBL1778636

SMILES: OC(=O)COc1ccc(Cl)cc1-c1cccc(c1)C#N

InChI Key: InChIKey=LKVOYKPVSRJIAP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50344994 (2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid |...) Show SMILES OC(=O)COc1ccc(Cl)cc1-c1cccc(c1)C#N Show InChI InChI=1S/C15H10ClNO3/c16-12-4-5-14(20-9-15(18)19)13(7-12)11-3-1-2-10(6-11)8-17/h1-7H,9H2,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assay				Bioorg Med Chem Lett 21: 3616-21 (2011) Article DOI: 10.1016/j.bmcl.2011.04.101 BindingDB Entry DOI: 10.7270/Q2S46S9Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50344994 (2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid |...) Show SMILES OC(=O)COc1ccc(Cl)cc1-c1cccc(c1)C#N Show InChI InChI=1S/C15H10ClNO3/c16-12-4-5-14(20-9-15(18)19)13(7-12)11-3-1-2-10(6-11)8-17/h1-7H,9H2,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Antagonist activity at human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-induced calcium flux in presence of 1% bovine serum...				Bioorg Med Chem Lett 21: 3616-21 (2011) Article DOI: 10.1016/j.bmcl.2011.04.101 BindingDB Entry DOI: 10.7270/Q2S46S9Z
					More data for this Ligand-Target Pair