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SMILES: Cc1ccc(cc1-c1cc(ccc1OCC(O)=O)C(F)(F)F)C#N

InChI Key: InChIKey=ITXSYJKPQOUJKF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344995   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50344995
PNG
(2-(5'-cyano-2'-methyl-5-(trifluoromethyl)biphenyl-...)
Show SMILES Cc1ccc(cc1-c1cc(ccc1OCC(O)=O)C(F)(F)F)C#N
Show InChI InChI=1S/C17H12F3NO3/c1-10-2-3-11(8-21)6-13(10)14-7-12(17(18,19)20)4-5-15(14)24-9-16(22)23/h2-7H,9H2,1H3,(H,22,23)
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Article
PubMed
n/an/a 0.200n/an/an/an/an/an/a



AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assay

Bioorg Med Chem Lett 21: 3616-21 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.101
BindingDB Entry DOI: 10.7270/Q2S46S9Z
More data for this
Ligand-Target Pair