BDBM50344999 2-(2'-chloro-4'-(N-methylmethylsulfonamido)-5-(trifluoromethyl)biphenyl-2-yloxy)acetic acid::CHEMBL1778632
SMILES: CN(c1ccc(c(Cl)c1)-c1cc(ccc1OCC(O)=O)C(F)(F)F)S(C)(=O)=O
InChI Key: InChIKey=USPKBVJAPGRDPR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50344999 (2-(2'-chloro-4'-(N-methylmethylsulfonamido)-5-(tri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assay | Bioorg Med Chem Lett 21: 3616-21 (2011) Article DOI: 10.1016/j.bmcl.2011.04.101 BindingDB Entry DOI: 10.7270/Q2S46S9Z | |||||||||||
More data for this Ligand-Target Pair |