BDBM50345079 (1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)(4-methyl-1,4-diazepan-1-yl)methanone::CHEMBL1779231
SMILES: COc1ccc(c(C)c1C)S(=O)(=O)n1c(C)c(C(=O)N2CCCN(C)CC2)c2ccccc12
InChI Key: InChIKey=JOJSTNFYLOFXMJ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V1b receptor (Homo sapiens (Human)) | BDBM50345079 ((1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
MSD Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cells | Bioorg Med Chem Lett 21: 3603-7 (2011) Article DOI: 10.1016/j.bmcl.2011.04.104 BindingDB Entry DOI: 10.7270/Q2833SCQ | |||||||||||
More data for this Ligand-Target Pair |