BDBM50345156 CHEMBL1779536
SMILES: Cc1c2CCCN3CC[C@@H](C3)CNc3cc(ccc3C(N)=O)-n2c2CC(C)(C)CC(=O)c12
InChI Key: InChIKey=HIBZKCZRHCXVEZ-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50345156 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50345156
(CHEMBL1779536)Show SMILES Cc1c2CCCN3CC[C@@H](C3)CNc3cc(ccc3C(N)=O)-n2c2CC(C)(C)CC(=O)c12 |r| Show InChI InChI=1S/C26H34N4O2/c1-16-21-5-4-9-29-10-8-17(15-29)14-28-20-11-18(6-7-19(20)25(27)32)30(21)22-12-26(2,3)13-23(31)24(16)22/h6-7,11,17,28H,4-5,8-10,12-15H2,1-3H3,(H2,27,32)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by HT patch clamp assay |
Bioorg Med Chem Lett 21: 3627-31 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.102
BindingDB Entry DOI: 10.7270/Q2VX0GVP |
More data for this
Ligand-Target Pair | |
Heat shock protein HSP 90-alpha
(Homo sapiens (Human)) | BDBM50345156
(CHEMBL1779536)Show SMILES Cc1c2CCCN3CC[C@@H](C3)CNc3cc(ccc3C(N)=O)-n2c2CC(C)(C)CC(=O)c12 |r| Show InChI InChI=1S/C26H34N4O2/c1-16-21-5-4-9-29-10-8-17(15-29)14-28-20-11-18(6-7-19(20)25(27)32)30(21)22-12-26(2,3)13-23(31)24(16)22/h6-7,11,17,28H,4-5,8-10,12-15H2,1-3H3,(H2,27,32)/t17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 201 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assay |
Bioorg Med Chem Lett 21: 3627-31 (2011)
Article DOI: 10.1016/j.bmcl.2011.04.102
BindingDB Entry DOI: 10.7270/Q2VX0GVP |
More data for this
Ligand-Target Pair | |
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