BDBM50345451 3-(2-Methyltetrahydrofuran-3-ylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile::CHEMBL1784722

SMILES: CC1OCCC1Sc1ccc2c3c(C#N)c(=O)nc3c3cccc1c23

InChI Key: InChIKey=MHPJAEWEVSPYJK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50345451 (3-(2-Methyltetrahydrofuran-3-ylthio)-8-oxo-8H-acen...) Show SMILES CC1OCCC1Sc1ccc2c3c(C#N)c(=O)nc3c3cccc1c23 Show InChI InChI=1S/C20H14N2O2S/c1-10-15(7-8-24-10)25-16-6-5-12-17-11(16)3-2-4-13(17)19-18(12)14(9-21)20(23)22-19/h2-6,10,15H,7-8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISA				J Med Chem 54: 3732-45 (2011) Article DOI: 10.1021/jm200258t BindingDB Entry DOI: 10.7270/Q29W0FTH
					More data for this Ligand-Target Pair