BDBM50345453 8-Oxo-3-(2-(thiazolidin-3-yl)ethylthio)-8H-acenaphtho-[1,2-b]pyrrole-9-carbonitrile::CHEMBL1784724

SMILES: O=c1nc2c3cccc4c(SCCN5CCSC5)ccc(c2c1C#N)c34

InChI Key: InChIKey=WABPZAXEMMYCEO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50345453 (8-Oxo-3-(2-(thiazolidin-3-yl)ethylthio)-8H-acenaph...) Show SMILES O=c1nc2c3cccc4c(SCCN5CCSC5)ccc(c2c1C#N)c34 Show InChI InChI=1S/C20H15N3OS2/c21-10-15-18-13-4-5-16(26-9-7-23-6-8-25-11-23)12-2-1-3-14(17(12)13)19(18)22-20(15)24/h1-5H,6-9,11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISA				J Med Chem 54: 3732-45 (2011) Article DOI: 10.1021/jm200258t BindingDB Entry DOI: 10.7270/Q29W0FTH
					More data for this Ligand-Target Pair