BDBM50345460 CHEMBL1784732::Ethyl 3-(1-(5-Methyl-1,3-oxathiolan-5-yl)ethylthio)-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxylate

SMILES: CCOC(=O)c1c2c3ccc(SC(C)C4(C)CSCO4)c4cccc(c2nc1=O)c34

InChI Key: InChIKey=IBCFLQFWCYTALG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50345460 (CHEMBL1784732 | Ethyl 3-(1-(5-Methyl-1,3-oxathiola...) Show SMILES CCOC(=O)c1c2c3ccc(SC(C)C4(C)CSCO4)c4cccc(c2nc1=O)c34 Show InChI InChI=1S/C23H21NO4S2/c1-4-27-22(26)19-18-14-8-9-16(30-12(2)23(3)10-29-11-28-23)13-6-5-7-15(17(13)14)20(18)24-21(19)25/h5-9,12H,4,10-11H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISA				J Med Chem 54: 3732-45 (2011) Article DOI: 10.1021/jm200258t BindingDB Entry DOI: 10.7270/Q29W0FTH
					More data for this Ligand-Target Pair