BDBM50345465 Allyl 8-Oxo-3-(propylthio)-8H-acenaphtho[1,2-b]pyrrole-9-carboxylate::CHEMBL1784737

SMILES: CCCSc1ccc2c3c(C(=O)OCC=C)c(=O)nc3c3cccc1c23

InChI Key: InChIKey=UXWHGXQWZJRHQR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50345465 (Allyl 8-Oxo-3-(propylthio)-8H-acenaphtho[1,2-b]pyr...) Show SMILES CCCSc1ccc2c3c(C(=O)OCC=C)c(=O)nc3c3cccc1c23 Show InChI InChI=1S/C21H17NO3S/c1-3-10-25-21(24)18-17-13-8-9-15(26-11-4-2)12-6-5-7-14(16(12)13)19(17)22-20(18)23/h3,5-9H,1,4,10-11H2,2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISA				J Med Chem 54: 3732-45 (2011) Article DOI: 10.1021/jm200258t BindingDB Entry DOI: 10.7270/Q29W0FTH
					More data for this Ligand-Target Pair