BDBM50345681 (3-endo)-1,1-Bis-(3-fluorophenyl)-2-(8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl)ethanol Iodide::CHEMBL1782095

SMILES: C[N+]1(C)[C@@H]2CC[C@@H]1CC(CC(O)(c1cccc(F)c1)c1cccc(F)c1)C2

InChI Key: InChIKey=HRJMEBQOMIUMNQ-FGZHOGPDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50345681 ((3-endo)-1,1-Bis-(3-fluorophenyl)-2-(8,8-dimethyl-...) Show SMILES C[N+]1(C)[C@@H]2CC[C@@H]1CC(CC(O)(c1cccc(F)c1)c1cccc(F)c1)C2 |r,THB:9:8:1:4.5| Show InChI InChI=1S/C23H28F2NO/c1-26(2)21-9-10-22(26)12-16(11-21)15-23(27,17-5-3-7-19(24)13-17)18-6-4-8-20(25)14-18/h3-8,13-14,16,21-22,27H,9-12,15H2,1-2H3/q+1/t21-,22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FLIPR				J Med Chem 52: 5241-52 (2010) Article DOI: 10.1021/jm900736e BindingDB Entry DOI: 10.7270/Q2PK0H54
					More data for this Ligand-Target Pair