BDBM50345685 (3-endo)-1,1-Bis(3-fluoro-2-methylphenyl)-2-(8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl)ethanol Bromide::CHEMBL1782099

SMILES: Cc1c(F)cccc1C(O)(CC1C[C@H]2CC[C@H](C1)[N+]2(C)C)c1cccc(F)c1C

InChI Key: InChIKey=XEXMASOMLCDSNZ-WOJBJXKFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50345685 ((3-endo)-1,1-Bis(3-fluoro-2-methylphenyl)-2-(8,8-d...) Show SMILES Cc1c(F)cccc1C(O)(CC1C[C@H]2CC[C@H](C1)[N+]2(C)C)c1cccc(F)c1C |r,TLB:10:11:18:14.15| Show InChI InChI=1S/C25H32F2NO/c1-16-21(7-5-9-23(16)26)25(29,22-8-6-10-24(27)17(22)2)15-18-13-19-11-12-20(14-18)28(19,3)4/h5-10,18-20,29H,11-15H2,1-4H3/q+1/t19-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FLIPR				J Med Chem 52: 5241-52 (2010) Article DOI: 10.1021/jm900736e BindingDB Entry DOI: 10.7270/Q2PK0H54
					More data for this Ligand-Target Pair