BDBM50345757 3-Chloro-1-(2,4-difluoro benzenesulfonyl)-5-(piperazin-1-yl-methyl)-1H-indole::CHEMBL1785071

SMILES: Fc1ccc(c(F)c1)S(=O)(=O)n1cc(Cl)c2cc(CN3CCNCC3)ccc12

InChI Key: InChIKey=YUKIKOBMXGRCTM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345757 (3-Chloro-1-(2,4-difluoro benzenesulfonyl)-5-(piper...) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)n1cc(Cl)c2cc(CN3CCNCC3)ccc12 Show InChI InChI=1S/C19H18ClF2N3O2S/c20-16-12-25(28(26,27)19-4-2-14(21)10-17(19)22)18-3-1-13(9-15(16)18)11-24-7-5-23-6-8-24/h1-4,9-10,12,23H,5-8,11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair