BDBM50345960 9-(2-Methyl-allylamino)-3-phenyl-3H-thieno[2,3-d:4,5-d']dipyrimidin-4-one::CHEMBL1784059

SMILES: CC(=C)CNc1ncnc2sc3c(ncn(-c4ccccc4)c3=O)c12

InChI Key: InChIKey=OUMPJKLCJUSVBG-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50345960 (9-(2-Methyl-allylamino)-3-phenyl-3H-thieno[2,3-d:4...) Show SMILES CC(=C)CNc1ncnc2sc3c(ncn(-c4ccccc4)c3=O)c12 Show InChI InChI=1S/C18H15N5OS/c1-11(2)8-19-16-13-14-15(25-17(13)21-9-20-16)18(24)23(10-22-14)12-6-4-3-5-7-12/h3-7,9-10H,1,8H2,2H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1				Bioorg Med Chem Lett 19: 3199-203 (2009) Article DOI: 10.1016/j.bmcl.2009.04.104 BindingDB Entry DOI: 10.7270/Q27081SJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50345960 (9-(2-Methyl-allylamino)-3-phenyl-3H-thieno[2,3-d:4...) Show SMILES CC(=C)CNc1ncnc2sc3c(ncn(-c4ccccc4)c3=O)c12 Show InChI InChI=1S/C18H15N5OS/c1-11(2)8-19-16-13-14-15(25-17(13)21-9-20-16)18(24)23(10-22-14)12-6-4-3-5-7-12/h3-7,9-10H,1,8H2,2H3,(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1				Bioorg Med Chem Lett 19: 3199-203 (2009) Article DOI: 10.1016/j.bmcl.2009.04.104 BindingDB Entry DOI: 10.7270/Q27081SJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50345960 (9-(2-Methyl-allylamino)-3-phenyl-3H-thieno[2,3-d:4...) Show SMILES CC(=C)CNc1ncnc2sc3c(ncn(-c4ccccc4)c3=O)c12 Show InChI InChI=1S/C18H15N5OS/c1-11(2)8-19-16-13-14-15(25-17(13)21-9-20-16)18(24)23(10-22-14)12-6-4-3-5-7-12/h3-7,9-10H,1,8H2,2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 19: 3199-203 (2009) Article DOI: 10.1016/j.bmcl.2009.04.104 BindingDB Entry DOI: 10.7270/Q27081SJ
					More data for this Ligand-Target Pair