null

SMILES: COc1ccc(cc1)-c1nc(C)c(CC=C)c(Nc2ccc(CC(O)=O)cc2)n1

InChI Key: InChIKey=BGZQSZZZEVNBPB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50346116 (2-(4-(5-allyl-2-(4-methoxyphenyl)-6-methylpyrimidi...) Show SMILES COc1ccc(cc1)-c1nc(C)c(CC=C)c(Nc2ccc(CC(O)=O)cc2)n1 Show InChI InChI=1S/C23H23N3O3/c1-4-5-20-15(2)24-22(17-8-12-19(29-3)13-9-17)26-23(20)25-18-10-6-16(7-11-18)14-21(27)28/h4,6-13H,1,5,14H2,2-3H3,(H,27,28)(H,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4D3 incubated for 10 mins using cAMP and [3H]cAMP substrates				Bioorg Med Chem Lett 19: 3174-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.121 BindingDB Entry DOI: 10.7270/Q26110NQ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50346116 (2-(4-(5-allyl-2-(4-methoxyphenyl)-6-methylpyrimidi...) Show SMILES COc1ccc(cc1)-c1nc(C)c(CC=C)c(Nc2ccc(CC(O)=O)cc2)n1 Show InChI InChI=1S/C23H23N3O3/c1-4-5-20-15(2)24-22(17-8-12-19(29-3)13-9-17)26-23(20)25-18-10-6-16(7-11-18)14-21(27)28/h4,6-13H,1,5,14H2,2-3H3,(H,27,28)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substrates				Bioorg Med Chem Lett 19: 3174-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.121 BindingDB Entry DOI: 10.7270/Q26110NQ
					More data for this Ligand-Target Pair