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BDBM50346173 2-(pyrimidin-5-ylmethyl)quinuclidine bis(2,2,2-trifluoroacetate)::CHEMBL1783882

SMILES: C(C1CC2CCN1CC2)c1cncnc1

InChI Key: InChIKey=UPYOGPXBFMUAMJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346173   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor protein alpha-7 subunit


(Mus musculus)		BDBM50346173
PNG
(2-(pyrimidin-5-ylmethyl)quinuclidine bis(2,2,2-tri...)
Show SMILES C(C1CC2CCN1CC2)c1cncnc1 |(25.75,-14.83,;27.08,-15.6,;28.41,-14.84,;29.74,-15.61,;29.74,-17.16,;28.39,-17.92,;27.07,-17.14,;28.58,-16.9,;28.12,-15.85,;24.41,-15.59,;24.41,-17.13,;23.08,-17.9,;21.75,-17.13,;21.75,-15.59,;23.08,-14.82,)|
Show InChI InChI=1S/C12H17N3/c1-3-15-4-2-10(1)5-12(15)6-11-7-13-9-14-8-11/h7-10,12H,1-6H2
PDB

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PC cid
PC sid
UniChem
Article
PubMed
 2.59E+3n/an/an/an/an/an/an/an/a



Targacept, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membrane

Bioorg Med Chem Lett 19: 4359-63 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.085
BindingDB Entry DOI: 10.7270/Q2DJ5FZP
More data for this
Ligand-Target Pair