BDBM50346218 5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-4-methylpyridin-2(1H)-one trifluoroacetate::CHEMBL1784121

SMILES: C[C@@H]1NC(=N[C@@]1(c1ccc(F)cc1)c1ccc(F)nc1)c1c[nH]c(=O)cc1C

InChI Key: InChIKey=QESCVXMWLWNAAE-ZSEKCTLFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50346218 (5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...) Show SMILES C[C@@H]1NC(=N[C@@]1(c1ccc(F)cc1)c1ccc(F)nc1)c1c[nH]c(=O)cc1C |r,c:3| Show InChI InChI=1S/C21H18F2N4O/c1-12-9-19(28)25-11-17(12)20-26-13(2)21(27-20,14-3-6-16(22)7-4-14)15-5-8-18(23)24-10-15/h3-11,13H,1-2H3,(H,25,28)(H,26,27)/t13-,21-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cells				Bioorg Med Chem 17: 6106-22 (2009) Article DOI: 10.1016/j.bmc.2009.05.069 BindingDB Entry DOI: 10.7270/Q2513ZHZ
					More data for this Ligand-Target Pair