BDBM50346348 CHEMBL1782649

SMILES: CN(C[C@@H]1COCCO1)S(=O)(=O)Nc1ccc2c(c1)ccc1ncc(cc1c2=O)-c1cnn(C)c1

InChI Key: InChIKey=DOAOECMTGWSJOZ-HXUWFJFHSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50346348 (CHEMBL1782649) Show SMILES CN(C[C@@H]1COCCO1)S(=O)(=O)Nc1ccc2c(c1)ccc1ncc(cc1c2=O)-c1cnn(C)c1 |r| Show InChI InChI=1S/C24H25N5O5S/c1-28-13-18(12-26-28)17-10-22-23(25-11-17)6-3-16-9-19(4-5-21(16)24(22)30)27-35(31,32)29(2)14-20-15-33-7-8-34-20/h3-6,9-13,20,27H,7-8,14-15H2,1-2H3/t20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	27.2	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to human unphosphorylated c-MET				Eur J Med Chem 46: 2043-57 (2011) Article DOI: 10.1016/j.ejmech.2011.02.057 BindingDB Entry DOI: 10.7270/Q2F47Q45
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50346348 (CHEMBL1782649) Show SMILES CN(C[C@@H]1COCCO1)S(=O)(=O)Nc1ccc2c(c1)ccc1ncc(cc1c2=O)-c1cnn(C)c1 |r| Show InChI InChI=1S/C24H25N5O5S/c1-28-13-18(12-26-28)17-10-22-23(25-11-17)6-3-16-9-19(4-5-21(16)24(22)30)27-35(31,32)29(2)14-20-15-33-7-8-34-20/h3-6,9-13,20,27H,7-8,14-15H2,1-2H3/t20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to human phosphorylated c-MET				Eur J Med Chem 46: 2043-57 (2011) Article DOI: 10.1016/j.ejmech.2011.02.057 BindingDB Entry DOI: 10.7270/Q2F47Q45
					More data for this Ligand-Target Pair