BDBM50346374 3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benzo[d][1,2,3]triazin-4(3H)-one::CHEMBL1783346
SMILES: O=c1n(CCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12
InChI Key: InChIKey=JQQXUGWNTUCGOI-UHFFFAOYSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50346374 (3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.000178 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli Federico II Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation counting | Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50346374 (3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli Federico II Curated by ChEMBL | Assay Description Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 mins | Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50346374 (3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli Federico II Curated by ChEMBL | Assay Description Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation counting | Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50346374 (3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli Federico II Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation counting | Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50346374 (3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benz...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli Federico II Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat frontal cortical homogenates after 15 mins | Eur J Med Chem 46: 2206-16 (2011) Article DOI: 10.1016/j.ejmech.2011.03.001 BindingDB Entry DOI: 10.7270/Q2M32W4J | |||||||||||
More data for this Ligand-Target Pair |