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BDBM50346477 CHEMBL1782989::endo-2-(3,4-dichlorophenyl)-1-(6-(pyrrolidin-1-yl)-1,4-diazabicyclo[3.3.1]nonan-4-yl)ethanone

SMILES: Clc1ccc(CC(=O)N2CCN3CC[C@@H]([C@H]2C3)N2CCCC2)cc1Cl

InChI Key: InChIKey=FUZIOWPRBHSDET-ZWKOTPCHSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346477   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50346477
PNG
(CHEMBL1782989 | endo-2-(3,4-dichlorophenyl)-1-(6-(...)
Show SMILES Clc1ccc(CC(=O)N2CCN3CC[C@@H]([C@H]2C3)N2CCCC2)cc1Cl |r|
Show InChI InChI=1S/C19H25Cl2N3O/c20-15-4-3-14(11-16(15)21)12-19(25)24-10-9-22-8-5-17(18(24)13-22)23-6-1-2-7-23/h3-4,11,17-18H,1-2,5-10,12-13H2/t17-,18+/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
73n/an/an/an/an/an/an/an/a



Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membranes after 150 mins by scintillation counting


Eur J Med Chem 46: 1972-82 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.064
BindingDB Entry DOI: 10.7270/Q2PV6KQ5
More data for this
Ligand-Target Pair