BDBM50346477 CHEMBL1782989::endo-2-(3,4-dichlorophenyl)-1-(6-(pyrrolidin-1-yl)-1,4-diazabicyclo[3.3.1]nonan-4-yl)ethanone

SMILES: Clc1ccc(CC(=O)N2CCN3CC[C@@H]([C@H]2C3)N2CCCC2)cc1Cl

InChI Key: InChIKey=FUZIOWPRBHSDET-ZWKOTPCHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50346477 (CHEMBL1782989 | endo-2-(3,4-dichlorophenyl)-1-(6-(...) Show SMILES Clc1ccc(CC(=O)N2CCN3CC[C@@H]([C@H]2C3)N2CCCC2)cc1Cl |r| Show InChI InChI=1S/C19H25Cl2N3O/c20-15-4-3-14(11-16(15)21)12-19(25)24-10-9-22-8-5-17(18(24)13-22)23-6-1-2-7-23/h3-4,11,17-18H,1-2,5-10,12-13H2/t17-,18+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membranes after 150 mins by scintillation counting				Eur J Med Chem 46: 1972-82 (2011) Article DOI: 10.1016/j.ejmech.2011.01.064 BindingDB Entry DOI: 10.7270/Q2PV6KQ5
					More data for this Ligand-Target Pair