BDBM50346561 CHEMBL1795604

SMILES: Cc1cnc2sn(-c3ccc(Br)cc3)c(=O)c2c1

InChI Key: InChIKey=BWZVJLYXJGXATI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase PCAF (Homo sapiens (Human))	BDBM50346561 (CHEMBL1795604) Show SMILES Cc1cnc2sn(-c3ccc(Br)cc3)c(=O)c2c1 Show InChI InChI=1S/C13H9BrN2OS/c1-8-6-11-12(15-7-8)18-16(13(11)17)10-4-2-9(14)3-5-10/h2-7H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair