BDBM50346586 CHEMBL1795981::US8765820, 5a

SMILES: NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1

InChI Key: InChIKey=INASJSARAJHICW-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50346586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50346586 (CHEMBL1795981 | US8765820, 5a) Show SMILES NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C17H18N2O2/c18-16-10-15(16)13-6-8-14(9-7-13)19-17(20)21-11-12-4-2-1-3-5-12/h1-9,15-16H,10-11,18H2,(H,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano US Patent					Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-...				US Patent US8765820 (2014) BindingDB Entry DOI: 10.7270/Q20P0XPN
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346586 (CHEMBL1795981 | US8765820, 5a) Show SMILES NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C17H18N2O2/c18-16-10-15(16)13-6-8-14(9-7-13)19-17(20)21-11-12-4-2-1-3-5-12/h1-9,15-16H,10-11,18H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of LSD1				Bioorg Med Chem 19: 3625-36 (2011) Article DOI: 10.1016/j.bmc.2011.01.046 BindingDB Entry DOI: 10.7270/Q23X870S
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346586 (CHEMBL1795981 | US8765820, 5a) Show SMILES NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C17H18N2O2/c18-16-10-15(16)13-6-8-14(9-7-13)19-17(20)21-11-12-4-2-1-3-5-12/h1-9,15-16H,10-11,18H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano US Patent					Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-...				US Patent US8765820 (2014) BindingDB Entry DOI: 10.7270/Q20P0XPN
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50346586 (CHEMBL1795981 | US8765820, 5a) Show SMILES NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C17H18N2O2/c18-16-10-15(16)13-6-8-14(9-7-13)19-17(20)21-11-12-4-2-1-3-5-12/h1-9,15-16H,10-11,18H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Inhibition of human LSD1				Bioorg Med Chem 19: 3709-16 (2011) Article DOI: 10.1016/j.bmc.2011.02.017 BindingDB Entry DOI: 10.7270/Q2J38SWT
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50346586 (CHEMBL1795981 | US8765820, 5a) Show SMILES NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C17H18N2O2/c18-16-10-15(16)13-6-8-14(9-7-13)19-17(20)21-11-12-4-2-1-3-5-12/h1-9,15-16H,10-11,18H2,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano US Patent					Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-...				US Patent US8765820 (2014) BindingDB Entry DOI: 10.7270/Q20P0XPN
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 2 (LSD2) (Mus musculus (Mouse))	BDBM50346586 (CHEMBL1795981 | US8765820, 5a) Show SMILES NC1CC1c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C17H18N2O2/c18-16-10-15(16)13-6-8-14(9-7-13)19-17(20)21-11-12-4-2-1-3-5-12/h1-9,15-16H,10-11,18H2,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Universita Degli Studi di Roma “La Sapienza”; Fondazione IEO; Universita Degli Studi di Pavia; Universita Degli Studi di Milano US Patent					Assay Description Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-...				US Patent US8765820 (2014) BindingDB Entry DOI: 10.7270/Q20P0XPN
					More data for this Ligand-Target Pair