BDBM50347531 CHEMBL1801633

SMILES: BrCC(=O)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12

InChI Key: InChIKey=FGPNDMIAMMFHFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50347531 (CHEMBL1801633) Show SMILES BrCC(=O)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12 |t:4| Show InChI InChI=1S/C14H9BrN2O3/c15-5-10(18)12-11(13(19)17-14(12)20)8-6-16-9-4-2-1-3-7(8)9/h1-4,6,16H,5H2,(H,17,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qui£?mica Medica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta using prephosphorylated polypeptide substrate after 30 mins by Glow-type luminescence assay in presence of 1...				J Med Chem 54: 4042-56 (2011) Article DOI: 10.1021/jm1016279 BindingDB Entry DOI: 10.7270/Q29887C1
					More data for this Ligand-Target Pair