BDBM50347687 CHEMBL1802828

SMILES: Cn1cc(cn1)-c1cnc2ccc3ccc(NS(=O)(=O)CCn4ccnc4)cc3c(=O)c2c1

InChI Key: InChIKey=MFOGSAOKLGJVCE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347687   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50347687 (CHEMBL1802828) Show SMILES Cn1cc(cn1)-c1cnc2ccc3ccc(NS(=O)(=O)CCn4ccnc4)cc3c(=O)c2c1 Show InChI InChI=1S/C23H20N6O3S/c1-28-14-18(13-26-28)17-10-21-22(25-12-17)5-3-16-2-4-19(11-20(16)23(21)30)27-33(31,32)9-8-29-7-6-24-15-29/h2-7,10-15,27H,8-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...				J Med Chem 54: 4092-108 (2011) Article DOI: 10.1021/jm200112k BindingDB Entry DOI: 10.7270/Q2X34ZFZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50347687 (CHEMBL1802828) Show SMILES Cn1cc(cn1)-c1cnc2ccc3ccc(NS(=O)(=O)CCn4ccnc4)cc3c(=O)c2c1 Show InChI InChI=1S/C23H20N6O3S/c1-28-14-18(13-26-28)17-10-21-22(25-12-17)5-3-16-2-4-19(11-20(16)23(21)30)27-33(31,32)9-8-29-7-6-24-15-29/h2-7,10-15,27H,8-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of c-MET overexpressed in human GTL-16 cells assessed as phosphorylation at C-terminal Y1349 after 2 hrs by Western blot analysis				J Med Chem 54: 4092-108 (2011) Article DOI: 10.1021/jm200112k BindingDB Entry DOI: 10.7270/Q2X34ZFZ
					More data for this Ligand-Target Pair