BDBM50347691 CHEMBL1802824

SMILES: O=c1c2cc(NS(=O)(=O)c3ccccc3)ccc2ccc2ncc(cc12)-c1ccccc1

InChI Key: InChIKey=QPITZSXYUYNGGX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50347691 (CHEMBL1802824) Show SMILES O=c1c2cc(NS(=O)(=O)c3ccccc3)ccc2ccc2ncc(cc12)-c1ccccc1 Show InChI InChI=1S/C26H18N2O3S/c29-26-23-16-21(28-32(30,31)22-9-5-2-6-10-22)13-11-19(23)12-14-25-24(26)15-20(17-27-25)18-7-3-1-4-8-18/h1-17,28H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...				J Med Chem 54: 4092-108 (2011) Article DOI: 10.1021/jm200112k BindingDB Entry DOI: 10.7270/Q2X34ZFZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50347691 (CHEMBL1802824) Show SMILES O=c1c2cc(NS(=O)(=O)c3ccccc3)ccc2ccc2ncc(cc12)-c1ccccc1 Show InChI InChI=1S/C26H18N2O3S/c29-26-23-16-21(28-32(30,31)22-9-5-2-6-10-22)13-11-19(23)12-14-25-24(26)15-20(17-27-25)18-7-3-1-4-8-18/h1-17,28H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of c-MET overexpressed in human GTL-16 cells assessed as phosphorylation at C-terminal Y1349 after 2 hrs by Western blot analysis				J Med Chem 54: 4092-108 (2011) Article DOI: 10.1021/jm200112k BindingDB Entry DOI: 10.7270/Q2X34ZFZ
					More data for this Ligand-Target Pair