BDBM50347696 CHEMBL1802604

SMILES: Cn1cc(cn1)-c1cnc2ccc3ccc(N)c(Cl)c3c(=O)c2c1

InChI Key: InChIKey=WXMLJXVNLBXZLH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50347696 (CHEMBL1802604) Show SMILES Cn1cc(cn1)-c1cnc2ccc3ccc(N)c(Cl)c3c(=O)c2c1 Show InChI InChI=1S/C18H13ClN4O/c1-23-9-12(8-22-23)11-6-13-15(21-7-11)5-3-10-2-4-14(20)17(19)16(10)18(13)24/h2-9H,20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...				J Med Chem 54: 4092-108 (2011) Article DOI: 10.1021/jm200112k BindingDB Entry DOI: 10.7270/Q2X34ZFZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50347696 (CHEMBL1802604) Show SMILES Cn1cc(cn1)-c1cnc2ccc3ccc(N)c(Cl)c3c(=O)c2c1 Show InChI InChI=1S/C18H13ClN4O/c1-23-9-12(8-22-23)11-6-13-15(21-7-11)5-3-10-2-4-14(20)17(19)16(10)18(13)24/h2-9H,20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of c-MET overexpressed in human GTL-16 cells assessed as phosphorylation at C-terminal Y1349 after 2 hrs by Western blot analysis				J Med Chem 54: 4092-108 (2011) Article DOI: 10.1021/jm200112k BindingDB Entry DOI: 10.7270/Q2X34ZFZ
					More data for this Ligand-Target Pair