BDBM50347703 CHEMBL261261
SMILES: Oc1ccc(\C=C2/CN(Cc3ccccc3)C\C(=C/c3ccc(O)c(Br)c3)C2=O)cc1Br
InChI Key: InChIKey=KNMFTTWVELIVCC-CLVAPQHMSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human)) | BDBM50347703 (CHEMBL261261) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of CARM1-mediated methylation of PABP1 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | J Med Chem 54: 4928-32 (2011) Article DOI: 10.1021/jm200453n BindingDB Entry DOI: 10.7270/Q2MK6D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SET domain-containing protein 7/9 (Set7/9) (Homo sapiens (Human)) | BDBM50347703 (CHEMBL261261) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >6.67E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of SET7-mediated methylation of histone H3 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | J Med Chem 54: 4928-32 (2011) Article DOI: 10.1021/jm200453n BindingDB Entry DOI: 10.7270/Q2MK6D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-arginine N-methyltransferase 1 (Homo sapiens (Human)) | BDBM50347703 (CHEMBL261261) | PDB B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >6.67E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of PRMT1-mediated methylation of NPL3 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine | J Med Chem 54: 4928-32 (2011) Article DOI: 10.1021/jm200453n BindingDB Entry DOI: 10.7270/Q2MK6D7F | |||||||||||
More data for this Ligand-Target Pair |