BDBM50347730 CHEMBL1802837

SMILES: OC\C=C\c1cccc(Nc2cnc3ccccc3n2)c1

InChI Key: InChIKey=YKSYKTRLMITDHY-GQCTYLIASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transforming protein RhoA (Homo sapiens (Human))	BDBM50347730 (CHEMBL1802837) Show SMILES OC\C=C\c1cccc(Nc2cnc3ccccc3n2)c1 Show InChI InChI=1S/C17H15N3O/c21-10-4-6-13-5-3-7-14(11-13)19-17-12-18-15-8-1-2-9-16(15)20-17/h1-9,11-12,21H,10H2,(H,19,20)/b6-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of rhoA expressed in Escherichia coli BL21 after 1 hr by G-LISA activation based chemiluminiscence assay				J Med Chem 54: 4508-22 (2011) Article DOI: 10.1021/jm200161c BindingDB Entry DOI: 10.7270/Q2C53M61
					More data for this Ligand-Target Pair