Found 6 hits for monomerid = 50347743 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
(RAT) | BDBM50347743
(CHEMBL1803082)Show SMILES CCNC1=NC(=Cc2ccc3OCOc3c2)C(=O)N1 |w:6.6,t:3| Show InChI InChI=1S/C13H13N3O3/c1-2-14-13-15-9(12(17)16-13)5-8-3-4-10-11(6-8)19-7-18-10/h3-6H,2,7H2,1H3,(H2,14,15,16,17) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description
Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation counting |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d
BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this
Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 2
(Homo sapiens (Human)) | BDBM50347743
(CHEMBL1803082)Show SMILES CCNC1=NC(=Cc2ccc3OCOc3c2)C(=O)N1 |w:6.6,t:3| Show InChI InChI=1S/C13H13N3O3/c1-2-14-13-15-9(12(17)16-13)5-8-3-4-10-11(6-8)19-7-18-10/h3-6H,2,7H2,1H3,(H2,14,15,16,17) | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation counting |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d
BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this
Ligand-Target Pair | |
Cyclin-Dependent Kinase 5 (CDK5)
(Homo sapiens (Human)) | BDBM50347743
(CHEMBL1803082)Show SMILES CCNC1=NC(=Cc2ccc3OCOc3c2)C(=O)N1 |w:6.6,t:3| Show InChI InChI=1S/C13H13N3O3/c1-2-14-13-15-9(12(17)16-13)5-8-3-4-10-11(6-8)19-7-18-10/h3-6H,2,7H2,1H3,(H2,14,15,16,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d
BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50347743
(CHEMBL1803082)Show SMILES CCNC1=NC(=Cc2ccc3OCOc3c2)C(=O)N1 |w:6.6,t:3| Show InChI InChI=1S/C13H13N3O3/c1-2-14-13-15-9(12(17)16-13)5-8-3-4-10-11(6-8)19-7-18-10/h3-6H,2,7H2,1H3,(H2,14,15,16,17) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant GST-tagged CLK3 using GRSRSRSRSRSR as substrate |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d
BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50347743
(CHEMBL1803082)Show SMILES CCNC1=NC(=Cc2ccc3OCOc3c2)C(=O)N1 |w:6.6,t:3| Show InChI InChI=1S/C13H13N3O3/c1-2-14-13-15-9(12(17)16-13)5-8-3-4-10-11(6-8)19-7-18-10/h3-6H,2,7H2,1H3,(H2,14,15,16,17) | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim1 |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d
BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50347743
(CHEMBL1803082)Show SMILES CCNC1=NC(=Cc2ccc3OCOc3c2)C(=O)N1 |w:6.6,t:3| Show InChI InChI=1S/C13H13N3O3/c1-2-14-13-15-9(12(17)16-13)5-8-3-4-10-11(6-8)19-7-18-10/h3-6H,2,7H2,1H3,(H2,14,15,16,17) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrate |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d
BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this
Ligand-Target Pair | |
Search and Browse
