Found 6 hits for monomerid = 50347767 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50347767
(CHEMBL1802850)Show SMILES CN1C(NC2CCCC2)=NC(=Cc2ccc3OCOc3c2)C1=O |w:11.12,c:9| Show InChI InChI=1S/C17H19N3O3/c1-20-16(21)13(19-17(20)18-12-4-2-3-5-12)8-11-6-7-14-15(9-11)23-10-22-14/h6-9,12H,2-5,10H2,1H3,(H,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrate |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50347767
(CHEMBL1802850)Show SMILES CN1C(NC2CCCC2)=NC(=Cc2ccc3OCOc3c2)C1=O |w:11.12,c:9| Show InChI InChI=1S/C17H19N3O3/c1-20-16(21)13(19-17(20)18-12-4-2-3-5-12)8-11-6-7-14-15(9-11)23-10-22-14/h6-9,12H,2-5,10H2,1H3,(H,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant GST-tagged CLK3 using GRSRSRSRSRSR as substrate |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 5 (CDK5)
(Homo sapiens (Human)) | BDBM50347767
(CHEMBL1802850)Show SMILES CN1C(NC2CCCC2)=NC(=Cc2ccc3OCOc3c2)C1=O |w:11.12,c:9| Show InChI InChI=1S/C17H19N3O3/c1-20-16(21)13(19-17(20)18-12-4-2-3-5-12)8-11-6-7-14-15(9-11)23-10-22-14/h6-9,12H,2-5,10H2,1H3,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this Ligand-Target Pair | |
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
(RAT) | BDBM50347767
(CHEMBL1802850)Show SMILES CN1C(NC2CCCC2)=NC(=Cc2ccc3OCOc3c2)C1=O |w:11.12,c:9| Show InChI InChI=1S/C17H19N3O3/c1-20-16(21)13(19-17(20)18-12-4-2-3-5-12)8-11-6-7-14-15(9-11)23-10-22-14/h6-9,12H,2-5,10H2,1H3,(H,18,19) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation counting |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this Ligand-Target Pair | |
Dual-specificity tyrosine-phosphorylation regulated kinase 2
(Homo sapiens (Human)) | BDBM50347767
(CHEMBL1802850)Show SMILES CN1C(NC2CCCC2)=NC(=Cc2ccc3OCOc3c2)C1=O |w:11.12,c:9| Show InChI InChI=1S/C17H19N3O3/c1-20-16(21)13(19-17(20)18-12-4-2-3-5-12)8-11-6-7-14-15(9-11)23-10-22-14/h6-9,12H,2-5,10H2,1H3,(H,18,19) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation counting |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50347767
(CHEMBL1802850)Show SMILES CN1C(NC2CCCC2)=NC(=Cc2ccc3OCOc3c2)C1=O |w:11.12,c:9| Show InChI InChI=1S/C17H19N3O3/c1-20-16(21)13(19-17(20)18-12-4-2-3-5-12)8-11-6-7-14-15(9-11)23-10-22-14/h6-9,12H,2-5,10H2,1H3,(H,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Pim1 |
J Med Chem 54: 4172-86 (2011)
Article DOI: 10.1021/jm200274d BindingDB Entry DOI: 10.7270/Q27D2VHR |
More data for this Ligand-Target Pair | |