BDBM50347875 CHEMBL1802783

SMILES: COCCCNc1nccc(n1)-c1c(C)[nH]c2ccc(Cl)cc12

InChI Key: InChIKey=NTXPFFQYJAPSSK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interferon-induced, double-stranded RNA-activated protein kinase (Homo sapiens (Human))	BDBM50347875 (CHEMBL1802783) Show SMILES COCCCNc1nccc(n1)-c1c(C)[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C17H19ClN4O/c1-11-16(13-10-12(18)4-5-14(13)21-11)15-6-8-20-17(22-15)19-7-3-9-23-2/h4-6,8,10,21H,3,7,9H2,1-2H3,(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay				Bioorg Med Chem Lett 21: 4108-14 (2011) Article DOI: 10.1016/j.bmcl.2011.04.149 BindingDB Entry DOI: 10.7270/Q2KK9C4H
					More data for this Ligand-Target Pair