BDBM50348086 CHEMBL1800484

SMILES: CC1(C)CC(CCNc2ccc(cc2)C#N)(CCO1)c1ccccc1

InChI Key: InChIKey=CLYVRUUIHVQWOQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human))	BDBM50348086 (CHEMBL1800484) Show SMILES CC1(C)CC(CCNc2ccc(cc2)C#N)(CCO1)c1ccccc1 Show InChI InChI=1S/C22H26N2O/c1-21(2)17-22(13-15-25-21,19-6-4-3-5-7-19)12-14-24-20-10-8-18(16-23)9-11-20/h3-11,24H,12-15,17H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Myrexis, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminal His6-tagged ICMT assessed as methylation of N-acetyl-S-geranylgeranylcysteine using SAM as methyl donor su...				J Med Chem 54: 5031-47 (2011) Article DOI: 10.1021/jm200249a BindingDB Entry DOI: 10.7270/Q2XW4K49
					More data for this Ligand-Target Pair