null

SMILES: Fc1ccc(cn1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1

InChI Key: InChIKey=FYDPOCATTVYCMF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50348498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50348498 (CHEMBL1801283) Show SMILES Fc1ccc(cn1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1 Show InChI InChI=1S/C21H17FN4O/c22-16-4-2-12(9-24-16)15-7-14-11(8-23-15)1-3-13-17-19(26-18(13)14)21(5-6-21)10-25-20(17)27/h2,4,7-9,26H,1,3,5-6,10H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of human MK2 using biotinyl-AYSRALSRQLSSGVSEIRCOOH as substrate after 45 mins by FRET analysis				Bioorg Med Chem Lett 20: 4719-23 (2010) Checked by Author Article DOI: 10.1016/j.bmcl.2010.04.023 BindingDB Entry DOI: 10.7270/Q2BZ66C2
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50348498 (CHEMBL1801283) Show SMILES Fc1ccc(cn1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1 Show InChI InChI=1S/C21H17FN4O/c22-16-4-2-12(9-24-16)15-7-14-11(8-23-15)1-3-13-17-19(26-18(13)14)21(5-6-21)10-25-20(17)27/h2,4,7-9,26H,1,3,5-6,10H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of MK2 mediated anisomycin-stimulated hsp27 phosphorylation in human THP-1 cells by fluorometric analysis				Bioorg Med Chem Lett 20: 4719-23 (2010) Checked by Author Article DOI: 10.1016/j.bmcl.2010.04.023 BindingDB Entry DOI: 10.7270/Q2BZ66C2
					More data for this Ligand-Target Pair