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SMILES: CCC(CC)Nc1nc(C)c(nc1C)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=IGARRFYCLVMEJA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348791   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50348791
PNG
(CHEMBL1807040)
Show SMILES CCC(CC)Nc1nc(C)c(nc1C)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C17H21Cl2N3/c1-5-13(6-2)22-17-11(4)20-16(10(3)21-17)14-8-7-12(18)9-15(14)19/h7-9,13H,5-6H2,1-4H3,(H,21,22)
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Article
PubMed
 27n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation counting

J Med Chem 54: 4187-206 (2011)


Article DOI: 10.1021/jm200365y
BindingDB Entry DOI: 10.7270/Q2XS5VR1
More data for this
Ligand-Target Pair