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SMILES: CCC(CC)Oc1nc(CC)c(nc1CC)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=XFFQPEYVHSNGRB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348803   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50348803
PNG
(CHEMBL1807028)
Show SMILES CCC(CC)Oc1nc(CC)c(nc1CC)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C19H24Cl2N2O/c1-5-13(6-2)24-19-17(8-4)22-18(16(7-3)23-19)14-10-9-12(20)11-15(14)21/h9-11,13H,5-8H2,1-4H3
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Article
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 46n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation counting

J Med Chem 54: 4187-206 (2011)


Article DOI: 10.1021/jm200365y
BindingDB Entry DOI: 10.7270/Q2XS5VR1
More data for this
Ligand-Target Pair