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SMILES: CCC(CC)Nc1nc(CC)c(nc1CC)-c1cnc(C)cc1N(C)C

InChI Key: InChIKey=UTIKVQPIYJNMDZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348813   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50348813
PNG
(CHEMBL1806957)
Show SMILES CCC(CC)Nc1nc(CC)c(nc1CC)-c1cnc(C)cc1N(C)C
Show InChI InChI=1S/C21H33N5/c1-8-15(9-2)23-21-18(11-4)24-20(17(10-3)25-21)16-13-22-14(5)12-19(16)26(6)7/h12-13,15H,8-11H2,1-7H3,(H,23,25)
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PubMed
 7.60n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation counting

J Med Chem 54: 4187-206 (2011)


Article DOI: 10.1021/jm200365y
BindingDB Entry DOI: 10.7270/Q2XS5VR1
More data for this
Ligand-Target Pair