BindingDB logo
myBDB logout

null

SMILES: CCC(CC)Nc1nc(CC)c(nc1CC)-c1ccc(OC(C)C)cc1OC

InChI Key: InChIKey=GZOXBGQDEGRMNO-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50348819   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50348819
PNG
(CHEMBL1806732)
Show SMILES CCC(CC)Nc1nc(CC)c(nc1CC)-c1ccc(OC(C)C)cc1OC
Show InChI InChI=1S/C23H35N3O2/c1-8-16(9-2)24-23-20(11-4)25-22(19(10-3)26-23)18-13-12-17(28-15(5)6)14-21(18)27-7/h12-16H,8-11H2,1-7H3,(H,24,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 4.20n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation counting

J Med Chem 54: 4187-206 (2011)


Article DOI: 10.1021/jm200365y
BindingDB Entry DOI: 10.7270/Q2XS5VR1
More data for this
Ligand-Target Pair