BDBM50349073 CHEMBL1807864

SMILES: COc1ccc2c(c1)sn(-c1ccc(Cl)cc1)c2=O

InChI Key: InChIKey=QVARFNHCTDWHGS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human))	BDBM50349073 (CHEMBL1807864) Show SMILES COc1ccc2c(c1)sn(-c1ccc(Cl)cc1)c2=O Show InChI InChI=1S/C14H10ClNO2S/c1-18-11-6-7-12-13(8-11)19-16(14(12)17)10-4-2-9(15)3-5-10/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Covalent inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using 4-hydroxyphenyl pyruvic acid as substrate asses...				Bioorg Med Chem Lett 26: 2764-2767 (2016) BindingDB Entry DOI: 10.7270/Q24X59PR
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human))	BDBM50349073 (CHEMBL1807864) Show SMILES COc1ccc2c(c1)sn(-c1ccc(Cl)cc1)c2=O Show InChI InChI=1S/C14H10ClNO2S/c1-18-11-6-7-12-13(8-11)19-16(14(12)17)10-4-2-9(15)3-5-10/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of human recombinant MIF tautomerase activity using 4-hydroxyphenylpyruvate as substrate				Bioorg Med Chem Lett 21: 4545-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.127 BindingDB Entry DOI: 10.7270/Q20K28Z3
					More data for this Ligand-Target Pair