BDBM50349311 CHEMBL1807841

SMILES: Cc1c(CCN2CCOCC2)c2cc(OCCF)ccc2n1C(=O)c1cccc(Cl)c1Cl

InChI Key: InChIKey=MUXUBRNSJROXHS-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50349311 (CHEMBL1807841) Show SMILES Cc1c(CCN2CCOCC2)c2cc(OCCF)ccc2n1C(=O)c1cccc(Cl)c1Cl Show InChI InChI=1S/C24H25Cl2FN2O3/c1-16-18(7-9-28-10-13-31-14-11-28)20-15-17(32-12-8-27)5-6-22(20)29(16)24(30)19-3-2-4-21(25)23(19)26/h2-6,15H,7-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IMIR K.U. Leuven Curated by ChEMBL					Assay Description Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells after 1 hrs by beta counting				Bioorg Med Chem 19: 4499-505 (2011) Article DOI: 10.1016/j.bmc.2011.06.033 BindingDB Entry DOI: 10.7270/Q22B8ZC7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50349311 (CHEMBL1807841) Show SMILES Cc1c(CCN2CCOCC2)c2cc(OCCF)ccc2n1C(=O)c1cccc(Cl)c1Cl Show InChI InChI=1S/C24H25Cl2FN2O3/c1-16-18(7-9-28-10-13-31-14-11-28)20-15-17(32-12-8-27)5-6-22(20)29(16)24(30)19-3-2-4-21(25)23(19)26/h2-6,15H,7-14H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IMIR K.U. Leuven Curated by ChEMBL					Assay Description Displacement of [3H]-SR141716A from human CB1 receptor expressed in CHO cells after 1 hrs by beta counting				Bioorg Med Chem 19: 4499-505 (2011) Article DOI: 10.1016/j.bmc.2011.06.033 BindingDB Entry DOI: 10.7270/Q22B8ZC7
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50349311 (CHEMBL1807841) Show SMILES Cc1c(CCN2CCOCC2)c2cc(OCCF)ccc2n1C(=O)c1cccc(Cl)c1Cl Show InChI InChI=1S/C24H25Cl2FN2O3/c1-16-18(7-9-28-10-13-31-14-11-28)20-15-17(32-12-8-27)5-6-22(20)29(16)24(30)19-3-2-4-21(25)23(19)26/h2-6,15H,7-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17.9	n/a	n/a	n/a	n/a
IMIR K.U. Leuven Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor expressed in CHO cells assessed as effect on [35S]-GTPgammaS binding after 1 hrs by beta counting				Bioorg Med Chem 19: 4499-505 (2011) Article DOI: 10.1016/j.bmc.2011.06.033 BindingDB Entry DOI: 10.7270/Q22B8ZC7
					More data for this Ligand-Target Pair