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BDBM50349335 CHEMBL1809240

SMILES: NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(=O)N2CCN(CC2)c2ncccn2)NS(=O)(=O)Cc2ccccc2)cc1

InChI Key: InChIKey=LDPGCQYXHHEKBS-SXOMAYOGSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349335   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 11D


(Homo sapiens (Human))		BDBM50349335
PNG
(CHEMBL1809240)
Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(=O)N2CCN(CC2)c2ncccn2)NS(=O)(=O)Cc2ccccc2)cc1 |r|
Show InChI InChI=1S/C32H39N9O5S/c33-29(34)25-11-9-23(10-12-25)21-37-30(43)27-8-4-15-41(27)31(44)26(38-47(45,46)22-24-6-2-1-3-7-24)20-28(42)39-16-18-40(19-17-39)32-35-13-5-14-36-32/h1-3,5-7,9-14,26-27,38H,4,8,15-22H2,(H3,33,34)(H,37,43)/t26-,27+/m1/s1
KEGG

UniProtKB/SwissProt

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Similars
Article
PubMed
 43n/an/an/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...

Bioorg Med Chem Lett 21: 4860-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M
More data for this
Ligand-Target Pair