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BDBM50349337 CHEMBL1809242

SMILES: Cc1ccc(C)c(c1)N1CCN(CC1)C(=O)C[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N

InChI Key: InChIKey=WUUKQSZMHJKYPC-JSOSNVBQSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349337   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 11D


(Homo sapiens (Human))		BDBM50349337
PNG
(CHEMBL1809242)
Show SMILES Cc1ccc(C)c(c1)N1CCN(CC1)C(=O)C[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r|
Show InChI InChI=1S/C36H45N7O5S/c1-25-10-11-26(2)32(21-25)41-17-19-42(20-18-41)33(44)22-30(40-49(47,48)24-28-7-4-3-5-8-28)36(46)43-16-6-9-31(43)35(45)39-23-27-12-14-29(15-13-27)34(37)38/h3-5,7-8,10-15,21,30-31,40H,6,9,16-20,22-24H2,1-2H3,(H3,37,38)(H,39,45)/t30-,31+/m1/s1
KEGG

UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
 73n/an/an/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...

Bioorg Med Chem Lett 21: 4860-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M
More data for this
Ligand-Target Pair